Explore how ubiquitin ligases regulate TGF-β signaling in keratinocytes and control subcutaneous adipose tissue accumulation in lymphatic dysfunction.
Discover how KRAS and TGF-β pathways collaborate through SIAH2 to drive cancer progression and metastasis in this comprehensive scientific analysis.
Discover how the HILI protein inhibits TGF-β signaling by interacting with Hsp90 and promoting TβR degradation in this groundbreaking cancer research.
Explore how targeting TGF-β regulated E3 ligases offers promising therapeutic strategies for primary liver cancer treatment.
Discover how silencing the PJA1 enzyme could revolutionize liver cancer treatment by restoring the TGF-β pathway's tumor-suppressing capabilities.